About Us

Alpha OV Therapeutics is dedicated to developing innovative oncolytic viral therapies that precisely target and destroy cancer cells, transforming patient outcomes.

Oncolytic Virus immunotherapy for Solid Tumors

We believe that combining innovative technology with clinical application is key to advancing cancer treatment. Our commitment includes:

  • Targeting Tumors, Protecting Health: Developing highly selective oncolytic viruses that attack tumors while minimizing harm to healthy tissues for safer, more effective treatments.
  • Activating the Immune System: Creating therapies that stimulate a lasting anti-cancer immune response, reducing recurrence and offering long-term benefits.
  • Improving Quality of Life: Reducing side effects to enhance patients’ well-being throughout treatment.
  • Driving Scientific Progress: Collaborating globally to translate cutting-edge research into clinical advances.

Vision: To lead globally in cancer treatment, delivering hope and breakthroughs for patients through innovation.


Action Mechanism of Oncolytic Virus

How oncolytic  virus  kills tumor cells

  • Selective Replication in Cancer CellsTarget
    • cancer cells due to altered signaling.
    • Exploit cancer cell vulnerabilities for replication.
  • Cell Lysis and Viral Release
    • Replicated virus causes cancer cell lysis.
    • Releases new viral particles into the tumor microenvironment.
  • Stimulation of Immune Responses
    • Viral components attract immune cells.
    • Induces a local immune response against cancer.
  • Anti-Angiogenic Effects
    • Inhibits angiogenesis, limiting tumor blood supply.
    • Impairs tumor growth by disrupting blood vessel formation.
  • Expression of Therapeutic Transgenes
    • Engineered to express therapeutic genes.
    • Enhances direct cytotoxic effects or modulates the immune response.
  • Clinical Implications
    • Used in cancer therapy, e.g., talimogene laherparepvec (T-VEC) for melanoma.
    • Demonstrates potential for targeted and immunotherapeutic cancer treatment.

Our Patents

Two patents are pending for Oncolytic Virus